Podocalyxin Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18150-1-AP

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HEK-293 cells, human kidney tissue, mouse kidney tissue, HepG2 cells

Positive IHC detected in:
human kidney tissue

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
podocalyxin-like

Calculated molecular weight:
526aa,55 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PODXL

Synonyms
GCTM 2 antigen, Gp200, PC, PCLP, PCLP 1, PCLP1, Podocalyxin, podocalyxin like, Podocalyxin like protein 1, PODXL, RCC marker, Renal Cell Carcinoma marker, TRA 1 81,TRA 1 60, TRA-1-60
Background

Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.


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