PPP2CA Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 13482-1-AP

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Freight/Packing

Con: 23 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, human liver tissue, MCF-7 cells

Positive IP detected in:
Hela cells, Jurkat cells

Positive IHC detected in:
human liver cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

Calculated molecular weight:
309aa,36 kDa

Observed molecular weight:
36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PPP2CA

Synonyms
PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C
Background

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.


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