PPP3CA-specific Fusion Protein

Catalog number: 55147-1-AP
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279.0000

Freight/Packing £00.00

Size: 09µ/gram

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Product Name:
PPP3CA-specific Rabbit Polyclonal antibody

Catalog No:
55147-1-AP

Source:
E. coli-derived, {{ptg:Vector}}

Peptide Sequence:
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({{ptg:AntigenPeptide}} encoded by NM_000944)

Activity:
Not tested.

Endotoxin Level:
Please contact the lab for more information.
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Formulation:
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{{ptg:Shipping}} and Storage


Reconstitution:
Reconstitute at {{ptg:SizeDesc}} sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage (see Stability and Storage for more details).
If a different concentration is needed for your purposes please adjust the reconstitution volume as required (please note: the ion concentration of the final solution will vary according to the volume used).
Note: Centrifuge vial before opening. When reconstituting, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution.

Shipping:
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Stability and Storage:
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Storage of Reconstituted Protein:
Short-term storage: Store at 2-8°C for two weeks.
Long-term storage: Aliquot and store at -20°C to -80°C for up to 6 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Background

PPP3CA, also called calcineurin Aα, is the only serine/threonine protein phosphatase under the control of Ca2+/calmodulin, and plays a critical role in the coupling of Ca2+ signals to cellular responses. Ca2+ signaling plays a central role in hypertrophic growth of cardiac and skeletal muscle in response to mechanical load and a variety of signals. Therefore, PPP3CA plays an important role in muscle differentiation, especially in muscle fiber type conversion. It is also involved in osteoclast regulation, regulating bone formation through an effect on osteoblast differentiation. This antibody is specific to PPP3CA.


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