RAB3GAP1 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 21663-1-AP

Featured Product KD/KO validated

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Con: 42 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat, monkey

Positive WB detected in:
HEK-293 cells, HL-60 cells, human brain tissue, mouse heart tissue, mouse kidney tissue

Positive IP detected in:
mouse kidney tissue

Positive IHC detected in:
human testis tissue, human kidney tissue

Positive IF detected in:
HepG2 cells, Hela cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
RAB3 GTPase activating protein subunit 1 (catalytic)

Calculated molecular weight:
981aa,111 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

KIAA0066, P130, Rab3 GAP, Rab3 GAP p130, RAB3 GTPase-activating protein 1, RAB3GAP, RAB3GAP1, RAB3GAP130, WARBM1

RAB3GAP1 (RAB3 GTPase-activating protein 1) is the catalytic subunit of the heterodimeric enzyme RAB3GAP (RAB3GTPase-activating protein), a key regulator of the RAB3 cycle, which controls calcium-mediated exocytosis of neurotransmitters and hormones. Mutations in RAB3GAP1 cause Warburg Micro syndrome (OMIM 600118) and Martsolf syndrome (OMIM 212720), phenotypically overlapping autosomal recessive conditions characterized by ocular and neurodevelopmental manifestations.

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