RDH10 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 14644-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human kidney tissue, A549 cells, HEK-293 cells, HepG2 cells, mouse kidney tissue, rat liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
RAW 264.7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
retinol dehydrogenase 10 (all-trans)

Calculated molecular weight:
38 kDa

Observed molecular weight:
39 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RDH10

Synonyms
RDH10, Retinol dehydrogenase 10, SDR16C4
Background

RDH10(Retinol dehydrogenase 10) is a strictly NAD+-dependent enzyme with multisubstrate specificity that recognizes cis-retinols as well as all-trans-retinol as substrates. RDH10-mediated oxidation of retinol plays as important a role in the control and regulation of RA production during embryogenesis as does the subsequent RALDH-mediated reaction(PMID: 22319578).


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