P-selectin Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60322-1-Ig |CloneNo.: 3G2C7

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Freight/Packing

Con: 162 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells

Positive IP detected in:
K-562 cells

Positive IHC detected in:
human spleen tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
selectin P (granule membrane protein 140kDa, antigen CD62)

Calculated molecular weight:
830aa,91 kDa

Observed molecular weight:
105-110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SELP

Synonyms
CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, P selectin, PADGEM, PSEL, P-selectin, SELP
Background

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.


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