SERPINA6 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12010-1-AP

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human plasma tissue, A375 cells, HEK-293 cells, L02 cells

Positive IHC detected in:
human kidney tissue, human hepatocirrhosis tissue, human kidney tissue, human liver tissue, human liver cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6

Calculated molecular weight:
405aa,45 kDa

Observed molecular weight:
45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SERPINA6

Synonyms
CBG, Serpin A6, SERPINA6, Transcortin
Background

SERPINA6, also known as corticosteroid-binding globulin or CBG, belongs to the serpin family of serine protease inhibitors, and is mainly secreted by the liver. It is an alpha-globulin protein with corticosteroid-binding properties, and involved in obesity and stress sensitivity. It is also the major transport protein for glucorticoids and progestins in the blood of most vertebrates. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency).


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