SNRPD1 Polyclonal antibody

SNRPD1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 10352-1-AP

Synonyms

HsT2456, Sm D autoantigen, Sm D1, SMD1, snRNP core protein D1, SNRPD, SNRPD1



Tested Applications

Positive WB detected inHEK-293 cells, HL-60 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 2 publications below

Product Information

10352-1-AP targets SNRPD1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SNRPD1 fusion protein Ag0364
Full Name small nuclear ribonucleoprotein D1 polypeptide 16kDa
Calculated molecular weight 16 kDa
Observed molecular weight 13 kDa
GenBank accession numberBC001721
Gene symbol SNRPD1
Gene ID (NCBI) 6632
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune diseases. SNRPD1 is one Sm components of the small nuclear ribonucleoprotein complexes(snRNPs). It's a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. This antibody detectes 13-16 kDa (SMD1) and 30 kDa (SMD1/SMD2 dimer form; PMID:15525645).

Protocols

Product Specific Protocols
WB protocol for SNRPD1 antibody 10352-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cell Chem Biol

Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer.

Authors - Li Wang
mouseWB

J Proteome Res

Signaling in insulin-secreting MIN6 pseudoislets and monolayer cells.

Authors - Chowdhury Azazul Islam AI