SRC Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 11097-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 30 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, hamster

Positive WB detected in:
Jurkat cells, A431 cells, CHO cells, COLO 320 cells, mouse brain tissue, SH-SY5Y cells

Positive IP detected in:
SH-SY5Y cells

Positive IHC detected in:
human breast cancer tissue, human brain tissue, human breast cancer tissue, human spleen tissue

Positive IF detected in:
A431 cells

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Calculated molecular weight:
60 kDa

Observed molecular weight:
55 kDa, 60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SRC

Synonyms
ASV, c SRC, p60 Src, pp60c src, Proto oncogene c Src, SRC, SRC1
Background

SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.


Back
to top