TAC1 Polyclonal antibody

TAC1 Polyclonal Antibody for IF, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 13839-1-AP

Synonyms

Hs.2563, Neuromedin L, NK2, NKA, NKNA, PPT, Protachykinin 1, Substance K Neuropeptide K, Substance P, SubstanceP, TAC1, TAC2, tachykinin, precursor 1, Tachykinin-1



Tested Applications

Positive IHC detected inmouse brain tissue, human brain tissue, human stomach tissue, human pancreas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IFSee 1 publications below

Product Information

13839-1-AP targets TAC1 in IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TAC1 fusion protein Ag4790
Full Name tachykinin, precursor 1
Calculated Molecular Weight 129 aa, 15 kDa
GenBank Accession NumberBC018047
Gene Symbol TAC1
Gene ID (NCBI) 6863
RRIDAB_10898173
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

achykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.TAC1 is an abbreviation for protachykinin 1, a protein that is encoded by the TAC1 gene, which is responsible for 4 products of the tachykinin peptide hormone family: substance P, neurokinin A, and the related peptides, neuropeptideK and neuropeptide (PMID:21453958).This antibody is specific to TAC1.

Protocols

Product Specific Protocols
IHC protocol for TAC1 antibody 13839-1-APDownload protocol
IF protocol for TAC1 antibody 13839-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse

Front Cell Neurosci

Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons.

Authors - Ali H Shaib
mouse

J Neuroimmunol

Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.

Authors - Yan Yu
human

Biomed Chromatogr

A new method for detecting Na+ , K+ -ATPase activity by ICP-MS: Quantitative analysis on the inhibitory effect of rhein on Na+ , K+ -ATPase activity by ICP-MS in HCT116 cells.

Authors - Hui Dai
rat

Exp Lung Res

Capsaicin pretreatment reversed pulmonary arterial hypertension by alleviating inflammation via p38MAPK pathway.

Authors - Ying Xu
IF

PLoS Genet

ZYG-9ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis

Authors - Gabriel Cavin-Meza