Transgelin 2 Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 10234-2-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human heart tissue, HEK-293 cells, T-47D cells

Positive IHC detected in:
human colon cancer tissue, human colon cancer tissue, human urothelial carcinoma tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transgelin 2

Calculated molecular weight:
199aa,22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TAGLN2

Synonyms
SM22 beta, SM22beta, TAGLN2, Transgelin 2
Background

The transgelin family is a group of proteins that belong to 22kd actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgenlin 2 protein. It may cross react with other two transgelins based on the sequence similarity.


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