TEAD1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 13283-1-AP

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Freight/Packing

Con: 34 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human skeletal muscle tissue

Positive IP detected in:
mouse skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
TEA domain family member 1 (SV40 transcriptional enhancer factor)

Calculated molecular weight:
426aa,47.9 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TEAD1

Synonyms
AA, NTEF 1, Protein GT IIC, REF1, TCF 13, TCF13, TEA domain family member 1, TEAD 1, TEAD1, TEF 1, TEF1, Transcription factor 13
Background

TEAD1 belongs to a protein family that share the TEA/ATTS domain. It acts as a transcriptional factor by binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also it can modulate SV40 late transcription together with large T antigen. The transcriptional activity of TEAD1 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary facotrs. TEAD1 also preforms an essential role in the Hippo signaling pathway. TEAD1 regulates gene rexpression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. TEAD is preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.


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