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TRAF6 Polyclonal antibody

TRAF6 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (3)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 12809-1-AP

Synonyms

RING finger protein 85, RNF85, TRAF6



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

12809-1-AP targets TRAF6 in WB, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse, rat, sheep
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRAF6 fusion protein Ag3555
Full Name TNF receptor-associated factor 6
Calculated molecular weight 522 aa, 60 kDa
GenBank accession numberBC031052
Gene symbol TRAF6
Gene ID (NCBI) 7189
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.

Publications

SpeciesApplicationTitle
ratWB

Ther Hypothermia Temp Manag

Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.

Authors - Xuan Jiang
humanWB

Int J Mol Med

Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.

Authors - Hui Wang
mouseWB

Int Immunopharmacol

Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.

Authors - Hong Yao
humanWB

Inflammation

Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway.

Authors - Yujue Wang
ratWB

J Ethnopharmacol

Influence of the Total Saponin Fraction from Dioscorea nipponica Makino on TLR2/4-IL1R Receptor Singnal Pathway in Rats of Gouty Arthritis.

Authors - Qi Zhou
sheepWB

Mediators Inflamm

Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.

Authors - Zhongjia Jiang