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- KD/KO Validated
TRAF6 Antibody
TRAF6 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (3)
Applications
WB, IF, ELISA
Conjugate
Unconjugated
Cat no : 12809-1-AP
Synonyms
RING finger protein 85, RNF85, TRAF6
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 12 publications below |
| IF | See 1 publications below |
Product Information
12809-1-AP targets TRAF6 in WB, IF, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse, rat, sheep |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TRAF6 fusion protein Ag3555 |
| Full Name | TNF receptor-associated factor 6 |
| Calculated molecular weight | 522aa,60 kDa |
| Observed molecular weight | |
| GenBank accession number | BC031052 |
| Gene symbol | TRAF6 |
| Gene ID (NCBI) | 7189 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.
Publications
| Species | Application | Title |
|---|---|---|
Ther Hypothermia Temp Manag Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass. | ||
Int J Mol Med Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders. | ||
Int Immunopharmacol Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway. | ||
Inflammation Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway. | ||
J Ethnopharmacol Influence of the Total Saponin Fraction from Dioscorea nipponica Makino on TLR2/4-IL1R Receptor Singnal Pathway in Rats of Gouty Arthritis. | ||
Mediators Inflamm Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells. |
