TRAF6 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 12809-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA, IF, WB
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Species specificity:
human, mouse, rat, sheep

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
TNF receptor-associated factor 6

Calculated molecular weight:
522aa,60 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TRAF6

Synonyms
RING finger protein 85, RNF85, TRAF6
Background

TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF6 is recognized as a signal transducer, which activates the NF-κB pathway in response to pro-inflammatory cytokines. TRAF6 has E3 ligase activity and is responsible for inducing Lys-63 (K63)-linked poly-ubiquitination chains, functioning together with E2 Ubc13/Uev1A complex to mediate IKK activation TRAF6 plays a crucial role in the regulation of the innate and adaptive immune responses.


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