TWIST2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11752-1-AP

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Freight/Packing

Con: 64 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
NIH/3T3 cells, MCF-7 cells, mouse liver tissue, NIH/3T3 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
twist homolog 2 (Drosophila)

Calculated molecular weight:
160aa,18 kDa

Observed molecular weight:
21kDa, 60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TWIST2

Synonyms
bHLHa39, Dermis expressed protein 1, Dermo 1, DERMO1, twist homolog 2 (Drosophila), Twist related protein 2, TWIST2
Background

TWIST2, also named as BHLHA39 and DERMO1,is a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. TWIST2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. It is also implicated in tumorigenesis, invasion and metastasis. TWIST2 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).


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