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UBE2W Polyclonal antibody

UBE2W Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF,ELISA

Conjugate

Unconjugated

Cat no : 15920-1-AP

Synonyms

hUBC 16, UBE2W, Ubiquitin carrier protein W, Ubiquitin protein ligase W



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

15920-1-AP targets UBE2W in WB, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UBE2W fusion protein Ag8729
Full Name ubiquitin-conjugating enzyme E2W (putative)
Calculated molecular weight 159 aa, 18 kDa
GenBank accession numberBC010900
Gene symbol UBE2W
Gene ID (NCBI) 55284
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

UBE2W(Ubiquitin-conjugating enzyme E2 W) is also named as UBC16. The deduced 162-amino acid protein has an approximately 150-amino acid catalytic core, termed the E2 ubiquitin-conjugating enzyme (UBC) domain, which contains 2 nuclear localization signals at its C-terminal end. RT-PCR detected ubiquitous UBC16 expression, with highest expression in heart, brain, liver, and pancreas(PMID:16368532). Ube2w can form nuclear homodimers(PMID:21229326). It has 3 isoforms produced by alternative splicing.

Publications

SpeciesApplicationTitle
humanWB, IF

Neurobiol Dis

The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin.

Authors - Bo Wang
  • KO Validated