You've been automatically redirected here from Humanzyme.com, which is now part of Proteintech Group. Click here to dismiss this alert.
  • HEK293 expressed
  • Endotoxin-free
  • Animal-component free

HumanKine® recombinant human IL-3 protein

Activity

Typically ≤ 2 ng/mL EC50

Species Reactivity

human

Purity

>95%

Cat no : HZ-1074

Synonyms

Hematopoietic growth factor, IL 3, IL3, IL-3, Interleukin 3, Mast cell growth factor, MCGF, MULTI CSF, P cell stimulating factor



Technical Specifications

GeneID 3562
Species human
Expression HEK293
Activity Typically ≤ 2 ng/mL EC50
Purity >95%
Molecular Mass 17 to 40 kDa, monomer, glycosylated
Formulation 1xPBS, See Certificate of Analysis for details
Species Reactivity human

Stability and Reconstitution

Stability and Storage Lyophilized proteins are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile I xPBS.

Background

Interleukin-3 (IL-3) is a multilineage hematopoietic growth factor that promotes the proliferation, differentiation and survival of early multilineage hematopoietic progenitors. In particular, this cytokine plays a key role in stimulating the proliferation and survival of myeloid precursors. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders (PMID: 24103757;2698876;2809196)

Synonyms

Hematopoietic growth factor, IL 3, IL3, IL-3, Interleukin 3, Mast cell growth factor, MCGF, MULTI CSF, P cell stimulating factor

Publications

SpeciesTitle
human

Haematologica

CD123 expression patterns and selective targeting with a CD123-specific antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia.

Authors - Evgeniya Angelova
human

Genet Mol Res

Impact of BMMSCs from different sources on proliferation of CD34⁺ cells.

Authors - R F Liu
human

Blood Res

Generation of hematopoietic stem cells from human embryonic stem cells using a defined, stepwise, serum-free, and serum replacement-free monolayer culture method.

Authors - So-JungKim
human

J Toxicol Sci

Human induced pluripotent stem cell-derived mast cells useful for in vitro mast cell activation assay exhibiting phenotypes and morphological characteristics of human mast cells.

Authors - Tatsuya Ikuno
human

PLoS One

A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.

Authors - Y TerryLee
human

J Tissue Eng Regen Med

Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium.

Authors - ColleenByrnes