- HEK293 expressed
- Endotoxin-free
- Animal-component free
HumanKine® recombinant human SCF protein
Activity(Primary)
15-85 ng/mL
Specific Activity
minimally 2.00 x 105 IU/mg
Species Reactivity
human
Purity
>95%
Cat no : HZ-1024
Synonyms
c Kit ligand, DKFZp686F2250, KIT ligand, Kitl, KITLG, KL 1, Mast cell growth factor, MGF, SCF, SF, SHEP7, Stem cell factor
Validation Data Gallery
Technical Specifications
| GeneID | 4254 |
| Species | Human |
| Expression | HEK293 |
| Activity(Primary) | 15-85 ng/mL |
| Specific Activity | minimally 2.00 x 105 IU/mg |
| Purity | >95% |
| Endotoxin | <1 EU/µg |
| Accession Number | P21583 |
| Molecular Mass | 30 to 45 kDa reduced and non-reduced, monomer, glycosylated |
| Formulation | 1x PBS, See Certificate of Analysis for details |
| Species Reactivity | human |
Stability and Reconstitution
| Stability and Storage | Product Form | Temperature Conditions | Storage Time (From Date of Receipt) |
|---|---|---|---|
| Lyophilized | -20°C to -80°C | Until Expiry Date | |
| Lyophilized | Room Temperature | 2 weeks | |
| Reconstituted as per CofA | -20°C to -80°C | 6 months | |
| Reconstituted as per CofA | 4°C | 1 week | |
| Avoid repeated freeze-thaw cycles. | |||
| Reconstitution | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein to 0.2 mg/mL in sterile 1xPBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA). Gently swirl or tap to mix. |
Background
SCF is a hematopoietic growth factor that works by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation, and differentiation of hematopoietic cells (PMID: 12773427)
Synonyms
c Kit ligand, DKFZp686F2250, KIT ligand, Kitl, KITLG, KL 1, Mast cell growth factor, MGF, SCF, SF, SHEP7, Stem cell factor
Publications
| Species | Title |
|---|---|
Blood LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo. | |
Dev Cell Defining the identity and the niches of epithelial stem cells with highly pleiotropic multilineage potency in the human thymus | |
Mol Cancer Ther IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML. | |
Stem Cells Brief report: efficient generation of hematopoietic precursors and progenitors from human pluripotent stem cell lines. | |
ACS Biomater Sci Eng Bioprinting of Human Cord Blood-Derived CD34+ Cells and Exploration of the Multilineage Differentiation Ability in Vitro. |
Reviews
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Clarisse (Verified Customer) (03-12-2025) | The product arrived very quickly, and the quality is excellent, making it ideal for my in vitro experiments. Reconstitution was straightforward following the CoA guidelines. I also appreciate the availability of a small-format option, which is perfect for preliminary tests and experiments.
|
FH marjolein (Verified Customer) (04-12-2024) | works as required
|