Antizyme inhibitor 1 Polyklonaler Antikörper

Antizyme inhibitor 1 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(13)

Kat-Nr. : 11548-1-AP

Synonyme

AZIN1, OAZIN, OAZI, AZIN 1, AZI1

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  WB analysis using 11548-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 11548-1-AP (Antizyme inhibitor 1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, HepG2-Zellen, NCI-H1299-Zellen, PC-3-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 10 publications below
• IHC: See 5 publications below
• IF: See 2 publications below

Produktinformation

11548-1-AP bindet in WB, IHC, IF, ELISA Antizyme inhibitor 1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Antizyme inhibitor 1 fusion protein Ag2082
• Vollständiger Name: antizyme inhibitor 1
• Berechnetes Molekulargewicht: 49.5 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC019279
• Gene symbol: AZIN1
• Gene ID (NCBI): 51582
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

AZIN1(Antizyme inhibitor 1) is also named as OAZI, OAZIN and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis, and playing a role in the regulation of polyamine synthesis (negative regulator of cellular polyamines).

Publikationen

Species	Application	Title
human	WB	Cancer Cell; The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers.; Authors - Leng Han
human	WB	J Clin Invest; Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma.; Authors - Anna Bianchi-Smiraglia
human	WB,IHC,IF	J Exp Clin Cancer Res; AZIN1 level is increased in medulloblastoma and correlates with c-Myc activity and tumor phenotype; Authors - Julie Sesen
human	WB	Mol Ther; Targeting RNA Editing of Antizyme Inhibitor 1: a Potential Oligonucleotide-Based Antisense Therapy for Cancer.; Authors - Daryl Jin Tai Tay
rat	WB	Theranostics; Crucial Role of miR-433 in Regulating Cardiac Fibrosis.; Authors - Lichan Tao
mouse	WB,IHC	Kidney Int; The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway.; Authors - Li Rong R