Bcl2 Monoklonaler Antikörper

Bcl2 Monoklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Maus und mehr (2)

Anwendung

WB, IF/ICC, IP, ELISA

Konjugation

Unkonjugiert

Publikationen(31)

CloneNo.

1B5B9

Kat-Nr. : 66799-1-Ig

Synonyme

Bcl-2, Bcl 2, B cell leukemia/lymphoma 2, 1B5B9



Geprüfte Anwendungen

Erfolgreiche Detektion in WBNIH/3T3-Zellen, 4T1-Zellen, C2C12-Zellen, Maushirngewebe, RAW 264.7-Zellen
Erfolgreiche Detektion in IF/ICCNIH/3T3-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
Immunfluoreszenz (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

66799-1-Ig bindet in WB, IF/ICC, IP, ELISA Bcl2 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
In Publikationen genannte Reaktivitäthuman, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Bcl2 fusion protein Ag24261
Vollständiger Name B-cell leukemia/lymphoma 2
Berechnetes Molekulargewicht 26 kDa
Beobachtetes Molekulargewicht 26 kDa
GenBank-ZugangsnummerNM-009741
Gene symbol Bcl2
Gene ID (NCBI) 12043
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Bcl2 is a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for Bcl2 antibody 66799-1-IgProtokoll herunterladen
IF protocol for Bcl2 antibody 66799-1-IgProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseWB

Circ Res

Endothelial FUNDC1 Deficiency Drives Pulmonary Hypertension

Authors - Yandong Pei
WB

Food Chem

Crosstalk between mitochondrial dysfunction and endoplasmic reticulum stress in apoptosis: Implications for grass carp flesh quality during cold storage

Authors - Xin Xiong
mouseWB

Phytomedicine

Puerarin prevents sepsis-associated encephalopathy by regulating the AKT1 pathway in microglia

Authors - Shao-Peng Lin
human,mouseWB

Biomed Pharmacother

Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice

Authors - Xiao-Hong Xiang

Redox Biol

Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload.

Authors - Chen Chen
mouseWB

Antioxidants (Basel)

Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress

Authors - Wenji Ren