CD31 Monoklonaler Antikörper

CD31 Monoklonal Antikörper für IF,FC

Wirt / Isotyp

Ratte / IgG2a

Getestete Reaktivität

Maus

Anwendung

IF, FC

Konjugation

Unkonjugiert

CloneNo.

390

Kat-Nr. : 65058-1-Ig

Synonyme

C85791, Cd31, Pecam, PECAM 1, Pecam1



Geprüfte Anwendungen

Erfolgreiche Detektion in IFbEnd.3-Zellen
Erfolgreiche Detektion in FCMaus-Splenozyten

Empfohlene Verdünnung

AnwendungVerdünnung
Immunfluoreszenz (IF)IF : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

IFSee 3 publications below

Produktinformation

65058-1-Ig bindet in IF, FC CD31 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Ratte / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen C3H/HeJ Maus hämatopoetische Vorläuferzelllinie 32D
Vollständiger Name platelet/endothelial cell adhesion molecule 1
GenBank-ZugangsnummerBC008519
Gene symbol Pecam1
Gene ID (NCBI) 18613
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer Borat-gepufferte Kochsalzlösung, pH 8,2.
LagerungsbedingungenBei 2-8℃ lagern.

Hintergrundinformationen

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

Protokolle

Produktspezifische Protokolle
IF protocol for CD31 antibody 65058-1-IgProtokoll herunterladen
FC protocol for CD31 antibody 65058-1-IgProtokoll herunterladen
Standard-Protokolle
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
IF

mBio

Human ApoE2 protects mice against Plasmodium berghei ANKA experimental cerebral malaria

Authors - Rui Liang
mouseIF

J Ethnopharmacol

Berberis dictyophylla F. inhibits angiogenesis and apoptosis of diabetic retinopathy via suppressing HIF-1α/VEGF/DLL-4/Notch-1 pathway.

Authors - Xiaopeng Ai
mouseIF

Adv Mater

Photothermal and Photocatalytic Glycol Chitosan and Polydopamine-Grafted Oxygen Vacancy Bismuth Oxyiodide (BiO1-x I) Nanoparticles for the Diagnosis and Targeted Therapy of Diabetic Wounds

Authors - Jianglong Kong