CD31 Monoklonaler Antikörper
CD31 Monoklonal Antikörper für IF/ICC, FC
Wirt / Isotyp
Ratte / IgG2a, kappa
Getestete Reaktivität
Maus
Anwendung
IF/ICC, FC
Konjugation
FITC Plus Fluorescent Dye
CloneNo.
390
Kat-Nr. : FITC-65058
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in IF/ICC | bEnd.3-Zellen |
Erfolgreiche Detektion in FC | Maus-Knochenmarkzellen |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
Immunfluoreszenz (IF)/ICC | IF/ICC : 1:50-1:500 |
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
IF | See 1 publications below |
FC | See 3 publications below |
Produktinformation
FITC-65058 bindet in IF/ICC, FC CD31 und zeigt Reaktivität mit Maus
Getestete Reaktivität | Maus |
In Publikationen genannte Reaktivität | Maus |
Wirt / Isotyp | Ratte / IgG2a, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | C3H/HeJ Maus hämatopoetische Vorläuferzelllinie 32D |
Vollständiger Name | platelet/endothelial cell adhesion molecule 1 |
GenBank-Zugangsnummer | BC008519 |
Gene symbol | CD31 |
Gene ID (NCBI) | 18613 |
Konjugation | FITC Plus Fluorescent Dye |
Excitation/Emission maxima wavelengths | 495 nm / 524 nm |
Form | Liquid |
Reinigungsmethode | Affinitätsreinigung |
Lagerungspuffer | PBS with 0.09% sodium azide |
Lagerungsbedingungen | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Hintergrundinformationen
Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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IF protocol for FITC Plus CD31 antibody FITC-65058 | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
Cell Death Dis LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease. | ||
Bone mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification | ||
Cells Enhancement of Tendon Repair Using Tendon-Derived Stem Cells in Small Intestinal Submucosa via M2 Macrophage Polarization | ||
Biochim Biophys Acta Mol Cell Res CARM1 deficiency inhibits osteoblastic differentiation of bone marrow mesenchymal stem cells and delays osteogenesis in mice |