CD31 Monoklonaler Antikörper

CD31 Monoklonal Antikörper für IF/ICC, FC

Wirt / Isotyp

Ratte / IgG2a, kappa

Getestete Reaktivität

Maus

Anwendung

IF/ICC, FC

Konjugation

FITC Plus Fluorescent Dye

Publikationen(4)

CloneNo.

390

Kat-Nr. : FITC-65058

Synonyme

PECAM-1, Pecam1, PECAM 1, Pecam, 390



Geprüfte Anwendungen

Erfolgreiche Detektion in IF/ICCbEnd.3-Zellen
Erfolgreiche Detektion in FCMaus-Knochenmarkzellen

Empfohlene Verdünnung

AnwendungVerdünnung
Immunfluoreszenz (IF)/ICCIF/ICC : 1:50-1:500
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

IFSee 1 publications below
FCSee 3 publications below

Produktinformation

FITC-65058 bindet in IF/ICC, FC CD31 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Ratte / IgG2a, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen C3H/HeJ Maus hämatopoetische Vorläuferzelllinie 32D
Vollständiger Name platelet/endothelial cell adhesion molecule 1
GenBank-ZugangsnummerBC008519
Gene symbol CD31
Gene ID (NCBI) 18613
Konjugation FITC Plus Fluorescent Dye
Excitation/Emission maxima wavelengths495 nm / 524 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer PBS with 0.09% sodium azide
LagerungsbedingungenStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
IF protocol for FITC Plus CD31 antibody FITC-65058Protokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseIF

Cell Death Dis

LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.

Authors - Hong Su
mouseFC

Bone

mTORC1 coordinates NF-κB signaling pathway to promote chondrogenic differentiation of tendon cells in heterotopic ossification

Authors - Jiaming Fu
FC

Cells

Enhancement of Tendon Repair Using Tendon-Derived Stem Cells in Small Intestinal Submucosa via M2 Macrophage Polarization

Authors - Xufeng Mao
mouseFC

Biochim Biophys Acta Mol Cell Res

CARM1 deficiency inhibits osteoblastic differentiation of bone marrow mesenchymal stem cells and delays osteogenesis in mice

Authors - Jing-Yi Li