CD68 Monoklonaler Antikörper

CD68 Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(13)

CloneNo.

3F10E11

Kat-Nr. : 66231-1-Ig

Synonyme

CD68, CD68 molecule, GP110, Macrosialin, SCARD1

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Geprüfte Anwendungen

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IHC: See 6 publications below
• IF: See 6 publications below

Produktinformation

66231-1-Ig bindet in WB, IHC, IF, ELISA CD68 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CD68 fusion protein Ag22815
• Vollständiger Name: CD68 molecule
• Berechnetes Molekulargewicht: 37 kDa
• GenBank-Zugangsnummer: BC015557
• Gene symbol: CD68
• Gene ID (NCBI): 968
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.

Publikationen

Species	Application	Title
human	IHC	Gastroenterology; NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.; Authors - Shuang Liang
mouse	IF	Redox Biol; Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy.; Authors - Xiaojuan Han
human	IHC	Cancer Immunol Immunother; CMTM6 expression in M2 macrophages is a potential predictor of PD-1/PD-L1 inhibitor response in colorectal cancer.; Authors - Xuehui Wu
human,mouse	IF	Am J Respir Cell Mol Biol; Lung Myofibroblast Promote Macrophage Pro-fibrotic Activity Through Lactate-induced Histone Lactylation.; Authors - Huachun Cui
human	IF	Front Immunol; Case Report: Dendritic Cells and Macrophages Capture Sperm in Chronically Inflamed Human Epididymis.; Authors - Wenzhong Zheng
human	WB	Biochem Pharmacol; Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer.; Authors - Xiaoliang Dong