Fabp4 Polyklonaler Antikörper

Fabp4 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (1)

Anwendung

WB, IF,ELISA

Konjugation

Unkonjugiert

Publikationen

2

Kat-Nr. : 51035-1-AP

Synonyme

422/aP2, ALBP/Ap2, Ap2, Fabp4, Lbpl

---

Galerie der Validierungsdaten

• 

  WB analysis of mouse skin using 51035-1-AP

  mouse skin tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse small intestine using 51035-1-AP

  mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 51035-1-AP

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 51035-1-AP (Fabp4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

---

Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 1 publications below

Produktinformation

51035-1-AP bindet in WB, IF,ELISA Fabp4 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: Hausschwein, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Fabp4 fusion protein Ag0712
• Vollständiger Name: fatty acid binding protein 4, adipocyte
• Berechnetes Molekulargewicht: 15 kDa
• Beobachtetes Molekulargewicht: 15 kDa
• GenBank-Zugangsnummer: BC054426
• Gene symbol: Fabp4
• Gene ID (NCBI): 11770
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20℃ lagern. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fatty acid binding protein (FABP) 4 is a member of the FABP family which abundantly expressed, fatty acid carrier proteins. FABPs are capable of binding a variety of hydrophobic molecules such as long-chain fatty acids and are important for their uptake and intracellular trafficking. It was first identified as an adipocyte-specific protein, important for the maintenance of lipid and glucose metabolism. It is also detected in macrophages, where it participates in regulating inflammation and cholesterol trafficking via NFκB and PPAR. In more recent studies, FABP4 has been found in a variety of endothelial cells, where it has been identified as a target of VEGF and a regulator of cell proliferation and possibly angiogenesis. Pathologically, FABP4 has been associated with the development of metabolic syndrome, diabetes and cancer and vulnerability of atherosclerotic plaques. FABP4 has been identified as a novel prognostic factor for both adverse cardiovascular events and breast cancer.

Publikationen

Species	Application	Title
mouse	IF	Cell; Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.; Authors - Daniel Kopinke
pig	WB	J Anim Sci; Antimicrobial peptide KR-32 alleviates Escherichia coli K88-induced fatty acid malabsorption by improving expression of FATP4.; Authors - H Liu