GDI2 Polyklonaler Antikörper

GDI2 Polyklonal Antikörper für IHC,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55096-1-AP

Synonyme

GDI 2, GDI2, GDP dissociation inhibitor 2, Rab GDI beta, RABGDIB

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Galerie der Validierungsdaten

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  IHC staining of human skin using 55096-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin using 55096-1-AP (GDI2 antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human skin using 55096-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin using 55096-1-AP (GDI2 antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human liver using 55096-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver using 55096-1-AP (GDI2 antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human liver using 55096-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver using 55096-1-AP (GDI2 antibody) at dilution of 1:50 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Hautgewebe, humanes Lebergewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

55096-1-AP bindet in IHC,ELISA GDI2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: GDP dissociation inhibitor 2
• Berechnetes Molekulargewicht: 51 kDa
• GenBank-Zugangsnummer: NM_001494
• Gene symbol: GDI2
• Gene ID (NCBI): 2665
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: 0,1 M NaHCO3, 0,1M Glyzin, 0,02% Natriumazid und 50% Glyzerin, pH 7,3.
• Lagerungsbedingungen: Bei -20℃ lagern. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GDP dissociation inhibitors (GDIs) are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, GDIs can bind and release GDP-bound Rab proteins from membranes. Two GDI proteins towards different Rab proteins have been identified. GDI1 interacts with almost all of the Rab proteins, while GDI2 interacts with Rabll but not Rab3A. GDI2 distributes ubiquitously, displaying a membrane bound location in perinuclear regions of cells. GDI-2 was thought to be involved in cellular response to insulin. It electrophoreses as a 46kd protein in SDS-PAGE. (PMID: 7929030; PMID: 19570034). The antibody is specific to GDI2. And it has no cross reaction to GDI1.