PROX1 Polyklonaler Antikörper

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• KD/KO Validated

PROX1 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (1)

Anwendung

WB, IHC, IF, CoIP, ChIP,ELISA

Konjugation

Unkonjugiert

Publikationen

10

Kat-Nr. : 51043-1-AP

Synonyme

prospero homeobox 1, Prospero homeobox protein 1, PROX 1, PROX1

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Galerie der Validierungsdaten

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  WB analysis of human brain using 51043-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 51043-1-AP (PROX1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rat brain using 51043-1-AP

  rat brain tissue were subjected to SDS PAGE followed by western blot with 51043-1-AP (PROX1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human lymphoma using 51043-1-AP

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 51043-1-AP (PROX1 antibody) at dilution of 1:50 (under 10x lens).

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 3 publications below
• WB: See 5 publications below
• IHC: See 2 publications below
• IF: See 2 publications below
• CoIP: See 2 publications below
• ChIP: See 2 publications below

Produktinformation

51043-1-AP bindet in WB, IHC, IF, CoIP, ChIP,ELISA PROX1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, hamster, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: PROX1 fusion protein Ag0457
• Vollständiger Name: prospero homeobox 1
• Berechnetes Molekulargewicht: 737 aa, 83 kDa
• Beobachtetes Molekulargewicht: 90 kDa
• GenBank-Zugangsnummer: BC024201
• Gene symbol: PROX1
• Gene ID (NCBI): 5629
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20℃ lagern. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

PROX1, Prospero homeobox protein 1, belongs to the Prospero homeobox family and contain a Prospero-type homeobox DNA-binding domain. PROX1 plays a fundamental role in early development of CNS and regulated the expression of gene and development of postmitotic undifferentiated young neuron. Also PROX1 is a specific and required regulator of the development of the lymphatic system. This is a rabbit polyclonal antibody raised against part of C-terminal chain of human PROX1.

Publikationen

Species	Application	Title
human,mouse	WB,CoIP,ChIP	Genes Dev; The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions.; Authors - Charest-Marcotte Alexis A ; KD Validated
mouse	CoIP,chIP	Nat Commun; An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.; Authors - Sean M Armour
human	WB	PLoS Genet; Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs.; Authors - Dufour Catherine R CR ; KD Validated
human	WB	Nucleic Acids Res; Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation.; Authors - Takeda Yukimasa Y ; KD Validated
human	IHC,IF	Am J Pathol; Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.; Authors - Jie-Gang Yang
human	IHC	PLoS One; Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma.; Authors - Tao Lv

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