RORC Polyklonaler Antikörper

RORC Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (2)

Anwendung

WB, IHC, IF, ChIP, ELISA

Konjugation

Unkonjugiert

Publikationen

24

Rezensionen (1)

Kat-Nr. : 13205-1-AP

Synonyme

NR1F3, Nuclear receptor ROR gamma, Nuclear receptor RZR gamma, Nuclear receptor RZR-gamma, RAR related orphan receptor C, ROR gamma T, RORC, RORG, RORyT, RORγt, RZR GAMMA, RZRG, TOR

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Galerie der Validierungsdaten

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  WB analysis of HEK-293 using 13205-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 13205-1-AP (RORC antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours.

• 

  WB analysis of Jurkat using 13205-1-AP

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13205-1-AP (RORC antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HEK-293-Zellen, Jurkat-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 18 publications below
• IHC: See 5 publications below
• IF: See 1 publications below
• ChIP: See 1 publications below

Produktinformation

13205-1-AP bindet in WB, IHC, IF, ChIP, ELISA RORC und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Hausschwein, Huhn, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RORC fusion protein Ag3961
• Vollständiger Name: RAR-related orphan receptor C
• Berechnetes Molekulargewicht: 518 aa, 58 kDa
• Beobachtetes Molekulargewicht: 58 kDa
• GenBank-Zugangsnummer: BC031554
• Gene symbol: RORC
• Gene ID (NCBI): 6097
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The Nuclear receptors retinoic acid receptor-related orphan receptor gamma (RORγ or RORc, also known as NR1F3) was the third and most recent ROR group member to be discovered, following the prior disclosures of RORα (RORa or NR1F1) and RORβ (RORb or NR1F2) (PMID:24502334). Studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.RORC has 2 isoforms with the MW of 56 kDa and 58 kDa.

Publikationen

Species	Application	Title
human	WB,ChIP	Oncogene; Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc; Authors - Ying-Nan Wang
rat	IF	Headache; Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis; Authors - Liu Yang
human	IHC	Front Oncol; Analysis of the potential association between ferroptosis and immune in hepatocellular carcinoma and their relationship with prognosis; Authors - Kai Wen
rat	WB	Biomed Pharmacother; Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.; Authors - Yu Xia
rat	WB	Phytomedicine; Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa; Authors - Yijun Tu
mouse	WB	Food Funct; Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.; Authors - Huichao Zhao

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Priya (Verified Customer) (06-21-2023)

Used this antibody for Caco2 cells andmice tissue

• Applications: Western Blot
• Primary Antibody Dilution: 1 to 1000
• Cell Tissue Type: Caco2, Mice colon