Anticorps Monoclonal anti-CD11b

CD11b Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2b, kappa

Réactivité testée

Humain, souris

Applications

FC

Conjugaison

CoraLite® Plus 405 Fluorescent Dye

CloneNo.

M1/70

N° de cat : CL405-65055

Synonymes

Cd11b, CD11b/CD18, CR3, CR3A, F730045J24Rik, integrin alpha M, Itgam, Ly 40, Mac 1, Mac 1a, MAC1



Applications testées

Résultats positifs en cytométriecellules médullaires de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL405-65055 cible CD11b dans les applications de FC et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Rat / IgG2b, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lymphocytes T spléniques de souris C57BL/10 et splénocytes C57BL/10 activés par la concanavaline A
Nom complet integrin alpha M
Numéro d’acquisition GenBankBC156991
Symbole du gène Itgam
Identification du gène (NCBI) 16409
Conjugaison CoraLite® Plus 405 Fluorescent Dye
Excitation/Emission maxima wavelengths399 nm / 422 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

Protocole

Product Specific Protocols
FC protocol for CL Plus 405 CD11b antibody CL405-65055Download protocol
Standard Protocols
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