Anticorps Monoclonal anti-CD3
CD3 Monoclonal Antibody for FC
Hôte / Isotype
Rat / IgG2b, kappa
Réactivité testée
souris
Applications
IF, FC
Conjugaison
FITC Plus Fluorescent Dye
CloneNo.
17A2
N° de cat : FITC-65077
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en cytométrie | splénocytes de souris, |
Dilution recommandée
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
IF | See 1 publications below |
FC | See 13 publications below |
Informations sur le produit
FITC-65077 cible CD3 dans les applications de IF, FC et montre une réactivité avec des échantillons souris
Réactivité | souris |
Réactivité citée | souris |
Hôte / Isotype | Rat / IgG2b, kappa |
Clonalité | Monoclonal |
Type | Anticorps |
Immunogène | Hybridome T-T γδTCR-positif D1 |
Nom complet | CD3 antigen, epsilon polypeptide |
Numéro d’acquisition GenBank | BC098236 |
Symbole du gène | CD3ε |
Identification du gène (NCBI) | 12501 |
Conjugaison | FITC Plus Fluorescent Dye |
Excitation/Emission maxima wavelengths | 495 nm / 524 nm |
Forme | Liquide |
Méthode de purification | Purification par affinité |
Tampon de stockage | PBS with 0.09% sodium azide |
Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Protocole
Product Specific Protocols | |
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FC protocol for FITC Plus CD3 antibody FITC-65077 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
ACS Appl Mater Interfaces Dual-Regulated Biomimetic Nanocomposites For Promoted Tumor Photodynamic Immunotherapy | ||
Phytomedicine Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma. | ||
Vet Microbiol An influenza virus vector candidate vaccine stably expressing SARS-CoV-2 receptor-binding domain produces high and long-lasting neutralizing antibodies in mice. | ||
Malar J Analysis of spleen histopathology, splenocyte composition and haematological parameters in four strains of mice infected with Plasmodium berghei K173. | ||
J Colloid Interface Sci Nano co-inducer of immunogenic cell death and ferroptosis for anti-tumor immunotherapy |