Anticorps Monoclonal anti-CD3

CD3 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2b, kappa

Réactivité testée

souris

Applications

IF, FC

Conjugaison

FITC Plus Fluorescent Dye

Publications(15)

CloneNo.

17A2

N° de cat : FITC-65077

Synonymes

AI504783, CD3, Cd3e, CD3epsilon, T3e



Applications testées

Résultats positifs en cytométriesplénocytes de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-65077 cible CD3 dans les applications de IF, FC et montre une réactivité avec des échantillons souris

Réactivité souris
Réactivité citéesouris
Hôte / Isotype Rat / IgG2b, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Hybridome T-T γδTCR-positif D1
Nom complet CD3 antigen, epsilon polypeptide
Numéro d’acquisition GenBankBC098236
Symbole du gène CD3ε
Identification du gène (NCBI) 12501
Conjugaison FITC Plus Fluorescent Dye
Excitation/Emission maxima wavelengths495 nm / 524 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).

Protocole

Product Specific Protocols
FC protocol for FITC Plus CD3 antibody FITC-65077Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
FC

Small

[Not Available]

Authors - Baochan Yang
mouseFC

ACS Appl Mater Interfaces

Dual-Regulated Biomimetic Nanocomposites For Promoted Tumor Photodynamic Immunotherapy

Authors - Li Liao
mouseFC

Phytomedicine

Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.

Authors - Li Wu
mouseFC

Vet Microbiol

An influenza virus vector candidate vaccine stably expressing SARS-CoV-2 receptor-binding domain produces high and long-lasting neutralizing antibodies in mice.

Authors - Yongzhen Zhao
mouseFC

Malar J

Analysis of spleen histopathology, splenocyte composition and haematological parameters in four strains of mice infected with Plasmodium berghei K173.

Authors - Huajing Wang
mouseFC

J Colloid Interface Sci

Nano co-inducer of immunogenic cell death and ferroptosis for anti-tumor immunotherapy

Authors - Guanhong Guo
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