Anticorps Polyclonal de lapin anti-F4/80
F4/80 Polyclonal Antibody for ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris et plus (1)
Applications
WB, IHC, ELISA
Conjugaison
Non conjugué
N° de cat : 18705-1-AP
Synonymes
Galerie de données de validation
Applications testées
Dilution recommandée
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| WB | See 3 publications below |
| IHC | See 17 publications below |
Informations sur le produit
18705-1-AP cible F4/80 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, souris
| Réactivité | Humain, souris |
| Réactivité citée | rat, Humain, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | Peptide |
| Nom complet | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 |
| Masse moléculaire calculée | 102 kDa |
| Numéro d’acquisition GenBank | BC075688 |
| Symbole du gène | Emr1 |
| Identification du gène (NCBI) | 13733 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Mouse F4/80, also named as EMR1 and Gpf480, is a 160kd cell surface glycoprotein which is a member of the EGF TM7 family. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. The function of F4/80 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages.
Publications
| Species | Application | Title |
|---|---|---|
EMBO J Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma. | ||
J Am Soc Nephrol Targeted Deletion of p53 in the Proximal Tubule Prevents Ischemic Renal Injury. | ||
Aging (Albany NY) Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition. | ||
Oncotarget Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation. | ||
Clin Sci (Lond) G-CSF partially mediates bone loss induced by Staphylococcus aureus infection in mice. | ||
Sci Rep New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats. |
