Tested Applications
| Positive WB detected in | HeLa cells, mouse spleen tissue, Jurkat cells, MCF-7 cells, MDA-MB-231 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:12000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
17784-1-AP targets ORC6 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11769 Product name: Recombinant human ORC6L protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-252 aa of BC063565 Sequence: MGSELIGRLAPRLGLAEPDMLRKAEEYLRLSRVKCVGLSARTTETSSAVMCLDLAASWMKCPLDRAYLIKLSGLNKETYQSCLKSFECLLGLNSNIGIRDLAVQFSCIEAVNMASKILKSYESSLPQTQQVDLDLSRPLFTSAALLSACKILKLKVDKNKMVATSGVKKAIFDRLCKQLEKIGQQVDREPGDVATPPRKRKKIVVEAPAKEMEKVEEMPHKPQKDEDLTQDYEEWKRKILENAASAQKATAE Predict reactive species |
| Full Name | origin recognition complex, subunit 6 like (yeast) |
| Calculated Molecular Weight | 252 aa, 28 kDa |
| Observed Molecular Weight | 28 kDa |
| GenBank Accession Number | BC063565 |
| Gene Symbol | ORC6 |
| Gene ID (NCBI) | 23594 |
| RRID | AB_2283320 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y5N6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for ORC6 antibody 17784-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The ORC6 Polyclonal antibody (Cat# 17784-1-AP) has 4 citations published in Advanced Science, Frontiers in Immunology, Aging (Albany NY), and Oncotarget. The associated research fields include non-small cell lung cancer (DNA damage and R-loop accumulation), tumor immune regulation and malignant progression, gastric adenocarcinoma prognostic signatures, and breast cancer apoptosis. All citations involve human samples using WB or IHC applications.
| Species | Application | Title |
|---|---|---|
Adv Sci (Weinh) Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA Damage | ||
Front Immunol Multi-omics analysis reveals the involvement of origin recognition complex subunit 6 in tumor immune regulation and malignant progression
| ||
Aging (Albany NY) Development and validation of a novel prognostic signature in gastric adenocarcinoma. | ||
Oncotarget The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis. |
