Tested Applications
| Positive IP detected in | mouse pancreas tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
26686-1-AP targets CYYR1 in WB, IP, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag24710 Product name: Recombinant human CYYR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 88-154 aa of BC036761 Sequence: MKNHRATRVGILRTTHINTVSSYPGPPPYGHDHEMEYCADLPPPYSPTPQGPAQRSPPPPYPGNARK Predict reactive species |
| Full Name | cysteine/tyrosine-rich 1 |
| Calculated Molecular Weight | 154 aa, 17 kDa |
| Observed Molecular Weight | 7-16 kDa |
| GenBank Accession Number | BC036761 |
| Gene Symbol | CYYR1 |
| Gene ID (NCBI) | 116159 |
| RRID | AB_3742199 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96J86 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
CYYR1 (Cysteine and tyrosine-rich protein 1) is characterized by a central cysteine- and tyrosine-rich domain, including a CCSYYAY box, and a proline-rich region at the carboxy-terminus with repeated PPPY motifs (PMID: 17442112). It is predicted to have a transmembrane domain and a signal peptide, suggesting it may be located in cell or cell compartment membranes (PMID: 17442112). CYYR1 has 6 isoforms, and the molecular weight ranges from 7kd to 16kd.
Protocols
| Product Specific Protocols | |
|---|---|
| IP protocol for CYYR1 antibody 26686-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The CYYR1 Polyclonal Antibody (Cat# 26686-1-AP) has 1 total citation. It appears in bioRxiv (2026), in a study investigating how fasting disrupts the InsP₆-HDAC3 axis to drive ER stress-mediated clearance of DNA-damaged cells and enforce tissue quality control. The research falls within the fields of cellular stress responses, DNA damage repair, and metabolic regulation. The antibody was used for Western blot in human and mouse samples.
| Species | Application | Title |
|---|---|---|
bioRxiv Fasting disrupts the InsP₆-HDAC3 axis to drive ER stress-mediated clearance of DNA-damaged cells and enforce tissue quality control. |
