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FCAMR/CD351 Polyclonal antibody (31929-1-AP)

FCAMR/CD351 Polyclonal antibody

FCAMR/CD351 Polyclonal Antibody for WB, ELISA

Cat No. 31929-1-AP

Review Product

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

CD351, Fc Alpha And Mu Receptor, Fc alpha/mu receptor, FCA/MR, Fcalpha/MuR

Formulation: PBS, Azide, Glycerol

PBS, Azide, Glycerol

Conjugate: Unconjugated

Unconjugated

Size/Concentration:

SKU:

-/ -

Freight/Packing: -

Quantity

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WB analysis using 31929-1-AP
Various lysates were subjected to SDS PAGE followed by western blot with 31929-1-AP (FCAMR antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
WB analysis using 31929-1-AP
Various lysates were subjected to SDS PAGE followed by western blot with 31929-1-AP (FCAMR antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Overview

Tested Applications
Product Information
Protocols

Print datasheet

MSDS SDS

Tested Applications

Positive WB detected in

human kidney tissue, mouse spleen tissue, mouse kidney tissue, mouse small intestine tissue, rat kidney tissue

Recommended dilution

Application	Dilution
Western Blot (WB)	WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31929-1-AP targets FCAMR/CD351 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity	human, mouse, rat
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag35303 Product name: Recombinant human FCAMR protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 17-170 aa of NM_001122979.2 Sequence: LPQKRPHPRWLWEGSLPSRTHLRAMGTLRPSSPLCWREESSFAAPNSLKGSRLVSGEPGGAVTIQCHYAPSSVNRHQRKYWCRLGPPRWICQTIVSTNQYTHHRYRDRVALTDFPQRGLFVVRLSQLSPDDIGCYLCGIGSENNMLFLSMNLTI Predict reactive species
Full Name	Fc receptor, IgA, IgM, high affinity
Calculated Molecular Weight	57 kDa
Observed Molecular Weight	60 kDa
GenBank Accession Number	NM_001122979.2
Gene Symbol	FCAMR
Gene ID (NCBI)	83953
RRID	AB_3670149
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity Purification
UNIPROT ID	Q8WWV6
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FCAMR, also known as CD351 or Fc α/µ receptor, is a type I transmembrane protein. Its extracellular region contains a short extracellular domain (EC) 1, an Ig variable (V) region-like EC2 domain and a stalk-like EC3 domain (PMID: 23182711). FCAMR is present in most B cells and macrophages and is a membrane surface protein that binds to the Fc fragment of IgA and IgM and induces endocytosis (PMID: 11779189). FCAMR may play a role in IgA- and IgM-mediated immune responses to microorganisms (PMID: 11062505).