TOM1L1 Polyclonal antibody

TOM1L1 Polyclonal Antibody for WB, ELISA

Cat No. 51017-1-AP

Publications (1)

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, ELISA

Synonyms

Src-activating and signaling molecule protein, Target of Myb-like protein 1, TOM1 L1, TOM1 like protein 1, TOM1L1 protein

Formulation: PBS, Azide, Glycerol

PBS, Azide, Glycerol

Conjugate: Unconjugated

Unconjugated

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WB analysis using 51017-1-AP
BT-474 cells were subjected to SDS PAGE followed by western blot with 51017-1-AP (TOM1L1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
WB analysis using 51017-1-AP
SGC-7901 cells were subjected to SDS PAGE followed by western blot with 51017-1-AP (TOM1L1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Overview

Tested Applications
Product Information
Publications (1)
Protocols

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MSDS SDS

Tested Applications

Positive WB detected in

BT-474 cells, SGC-7901 cells

Recommended dilution

Application	Dilution
Western Blot (WB)	WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

51017-1-AP targets TOM1L1 in WB, IP, ELISA applications and shows reactivity with human samples.

Tested Reactivity	human
Cited Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CatNo: Ag0502 Product name: Recombinant human TOM1L1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 381-1/1 of BC029396 Sequence: Predict reactive species
Full Name	target of myb1 (chicken)-like 1
Calculated Molecular Weight	476 aa, 53 kDa
Observed Molecular Weight	53 kDa
GenBank Accession Number	BC029396
Gene Symbol	TOM1L1
Gene ID (NCBI)	10040
RRID	AB_2207419
Conjugate	Unconjugated
Form	Liquid
Purification Method	Antigen affinity purification
UNIPROT ID	O75674
Storage Buffer	PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions	Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Target of Myb-like protein 1 (TOM1L1), also known as Srcasm, belongs to the Tom family. TOM1L1 encodes an adaptor protein characterized by an N-terminal VHS domain and a central GAT domain, which facilitates interactions with clathrin and components of the endosomal sorting machinery. Functionally, TOM1L1 serves as a substrate for Src family kinases, playing a regulatory role in growth factor signaling and membrane trafficking. It is involved in endocytosis, signal transduction, and the negative regulation of mitotic cell division. (PMID: 17977829, PMID: 26899482, PMID: 35238864, PMID: 39548458)

Protocols

Product Specific Protocols
WB protocol for TOM1L1 antibody 51017-1-AP	Download protocol

Standard Protocols
Click here to view our Standard Protocols

Publications

What published studies show

The TOM1L1 Polyclonal antibody (Cat# 51017-1-AP) has 1 total citation. It appears in Experimental Cell Research (2022), used for WB and IP in human samples. The cited study investigates mechanisms underlying melanoma invasion following MLK3 loss, placing this antibody within the research fields of cancer biology and cell signaling.