Tested Applications
| Positive WB detected in | MCF-7 cells, HeLa cells |
| Positive IHC detected in | human kidney tissue, human breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | HEK-293 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:100-1:400 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
55335-1-AP targets STK38 in WB, IHC, IF/ICC, IP, CoIP, IP-MS, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | serine/threonine kinase 38 |
| Calculated Molecular Weight | 54 kDa |
| Observed Molecular Weight | 54 kDa |
| GenBank Accession Number | NM_007271 |
| Gene Symbol | STK38 |
| Gene ID (NCBI) | 11329 |
| RRID | AB_2881310 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q15208 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Serine/threonine-protein kinase 38 belongs to AGC Ser/Thr protein kinase family.STK38 implicates in cell proliferation and/or tumor progression, and might play a role in the HIV-1 life cycle.Researches showed that STK38 with STK38L, were proapoptotic kinases and key members of the RASSF1/STK4 signaling cascade and its kinase activity increased in early mitotic phase and was dependent on FRY and STK3.This antibody recognizes the C-terminal of STK38.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for STK38 antibody 55335-1-AP | Download protocol |
| IHC protocol for STK38 antibody 55335-1-AP | Download protocol |
| WB protocol for STK38 antibody 55335-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
STK38 Polyclonal antibody (Cat# 55335-1-AP) has 7 citations published in Nature Communications, Cell Death & Differentiation, Cell Death & Disease, Cell Reports, Chemical Biology & Interactions, Journal of Proteome Research, and Journal of Cellular Biochemistry. The research spans innate immunity, necroptosis regulation, Hedgehog pathway signaling in renal carcinoma, antifungal host defense, hepatocellular carcinoma metabolism, lung adenocarcinoma metastasis, and prostate cancer Wnt/β-catenin signaling.
| Species | Application | Title |
|---|---|---|
Nat Commun A bacterial autotransporter impairs innate immune responses by targeting the transcription factor TFE3 | ||
Cell Death Differ Species-specific regulation of necroptosis by STK38-dependent RIPK1 phosphorylation. | ||
Cell Death Dis STK38-mediated feedback loop regulation of the hedgehog pathway governing tumor heterogeneity in renal papillary carcinoma.
| ||
Chem Biol Interact 6H2L, a novel derivative of bifendate, dually suppresses glycolysis and glutaminolysis in hepatocellular carcinoma via inhibiting YAP stability.
| ||
J Proteome Res ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis |
Reviews
What customers say
The single review for 55335-1-AP is from Raymond Ho (January 2026), who used it at a 1:100 dilution on stomach tissue for both immunohistochemistry and immunofluorescence. He rated the product 5 out of 5 stars and simply noted that it "works well." Overall, the feedback is positive, confirming reliable performance across two applications on human tissue.
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
Raymond (Verified Customer) (01-26-2026) | works well
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