Tested Applications
| Positive WB detected in | HeLa cells, human placenta tissue, LNCaP cells, pig rectum tissue, rat rectum tissue, HepG2 cells, JAR cells |
| Positive IF/ICC detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:400-1:1600 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
67706-1-Ig targets LAMC1 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
| Tested Reactivity | human, mouse, rat, pig |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag14674 Product name: Recombinant human LAMC1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1260-1609 aa of NM_002293.3 Sequence: AGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP Predict reactive species |
| Full Name | laminin, gamma 1 (formerly LAMB2) |
| Calculated Molecular Weight | 178 kDa |
| Observed Molecular Weight | 200-220 kDa |
| GenBank Accession Number | NM_002293.3 |
| Gene Symbol | LAMC1 |
| Gene ID (NCBI) | 3915 |
| RRID | AB_2882897 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P11047 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for LAMC1 antibody 67706-1-Ig | Download protocol |
| WB protocol for LAMC1 antibody 67706-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The LAMC1 Monoclonal antibody (1G2G4), catalog number 67706-1-Ig, has 7 total citations. These appear in journals including Journal of Pharmaceutical Analysis, Journal of Translational Medicine, Experimental Neurology, Rheumatology (Oxford), Vascular Pharmacology, Neuroscience, and BBA Molecular and Cellular Research. The research fields span metabolic liver disease (MASLD), glioma prognosis and cuproptosis, neuronal apoptosis after subarachnoid hemorrhage, melanoma autoantibodies, cardiac vascular smooth muscle cell lineage tracing, and stress-induced depression/anxiety in the olfactory system.
| Species | Application | Title |
|---|---|---|
J Pharm Anal Signatures of proteomics and glycoproteomics revealed liraglutide ameliorates MASLD by regulating specific metabolic homeostasis in mice. | ||
J Transl Med HIF-1α-mediated LAMC1 overexpression is an unfavorable predictor of prognosis for glioma patients: evidence from pan-cancer analysis and validation experiments | ||
Exp Neurol LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT signaling pathway after subarachnoid hemorrhage | ||
Rheumatology (Oxford) The central helicase domain holds the major conformational epitopes of melanoma differentiation-associated gene 5 autoantibodies | ||
Vascul Pharmacol Single-cell lineage tracing unveils sex differences in VSMCs derived from the cardiac neural crest and second heart field. | ||
Neuroscience Comparative Proteomics of Rat Olfactory Bulb Reveal Insights into Susceptibility and Resiliency to Chronic-stress-induced Depression or Anxiety. |
