Product Information
85622-2-PBS targets NGFR/TNFRSF16 as part of a matched antibody pair:
MP02004-1: 85622-3-PBS capture and 85622-2-PBS detection (validated in Cytometric bead array)
MP02004-2: 85622-2-PBS capture and 85622-1-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Recombinant protein Predict reactive species |
| Full Name | nerve growth factor receptor (TNFR superfamily, member 16) |
| Calculated Molecular Weight | 46 kDa |
| Observed Molecular Weight | 70-75 kDa |
| GenBank Accession Number | NM_033217.3 |
| Gene Symbol | Ngfr |
| Gene ID (NCBI) | 18053 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9Z0W1-1 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
p75NTR, also named TNFRSF16, Gp80-LNGFR, p75 ICD, and CD271, is a low-affinity receptor that can bind to NGF, BDNF, NT-3, and NT-4. It mediates cell survival as well as the cell death of neural cells. The antibody is specific to NGFR.
