14-3-3E Monoclonal antibody, PBS Only

14-3-3E Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66946-1-PBS
Clone No.3A3A4

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

14-3-3 epsilon, YWHAE, 14-3-3 protein epsilon, 14-3-3epsilon

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

66946-1-PBS targets 14-3-3E in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen

CatNo: Ag25186

Product name: Recombinant human 14-3-3E protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-255 aa of BC000179

Sequence: MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGDGEEQNKEALQDVEDENQ

Predict reactive species
Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Calculated Molecular Weight 255 aa, 29 kDa
Observed Molecular Weight 28-32 kDa
GenBank Accession NumberBC000179
Gene Symbol 14-3-3E
Gene ID (NCBI) 7531
RRIDAB_2882270
Conjugate Unconjugated
FormLiquid
Purification MethodProtein A purification
UNIPROT IDP62258
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

14-3-3 epsilon (also known as YWHAE) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis.

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