2019 n-COV membrane glycoprotein Polyclonal antibody

2019 n-COV membrane glycoprotein Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

virus

Applications

ELISA

Conjugate

Unconjugated

Cat no : 28882-1-AP

Synonyms

2019-nCOV membrane glycoprotein, M protein, membrane glycoprotein



Tested Applications

Positive ELISA detected inRecombinant protein

Recommended dilution

ApplicationDilution
Enzyme-linked Immunosorbent Assay (ELISA)ELISA :
Sample-dependent, check data in validation data gallery

Product Information

28882-1-AP targets 2019 n-COV membrane glycoprotein in ELISA applications and shows reactivity with virus samples.

Tested Reactivity virus
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen 2019 n-COV membrane glycoprotein fusion protein Ag30691
Full Name COVID-19 M Protein
GenBank accession numberNC_045512
Gene symbol COVID-19 M Protein
Gene ID (NCBI) 43740571
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

In the coronaviruses, the membrane (M) protein was reported to be the most abundant viral protein expressed during infection and a key protein in the assembly of both naked and enveloped virus particles (PMID: 11967315). The M glycoprotein is conserved across the β-coronaviruses. The multiple sequence alignment shows a remarkable similarity (98% identity) among the Sars-CoV-2 M variants and the sequences from Bat and Pangolin isolates (PMID:32596311). The M protein is predicted to contain a triple-spanning transmembrane (TM) region, a single N-glycosylation site near its N-terminus that is in the exterior of the virion, and a long C-terminal region in the interior (PMID: 15626342).