Product Information
23494-1-AP targets ADAM18 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag18672 Product name: Recombinant human ADAM18 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 338-687 aa of BC121045 Sequence: LRATCIMNHEAVSASGRKIFSNCSMHDYRYFVSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLKGSVKCGSGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNGRLCKLGTAYCYNGQCQTTDNQCAKIFGKGAQGAPFACFKEVNSLHERSENCGFKNSQPLPCERKDVLCGKLACVQPHKNANKSDAQSTVYSYIQDHVCVSIATGSSMRSDGTDNAYVADGTMCGPEMYCVNKTCRKVHLMGYNCNATTKCKGKGICNNFGNCQCFPGHRPPDCKFQFGSPGGSIDDGNFQKSGDFYTEKGYNTHWNN Predict reactive species |
| Full Name | ADAM metallopeptidase domain 18 |
| Calculated Molecular Weight | 739 aa, 83 kDa |
| GenBank Accession Number | BC121045 |
| Gene Symbol | ADAM18 |
| Gene ID (NCBI) | 8749 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9Y3Q7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ADAM18(Disintegrin and metalloproteinase domain-containing protein 18) is also named as TMDC3. It is a sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein. It has a tripeptide motif (ECD) within disintegrin-like domain, which could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding. The fuli length protein has 12 glycosylation sites, a signal peptide and a propeptide.
