Product Information
20755-1-PBS targets ADAM20 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag14493 Product name: Recombinant human ADAM20 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 492-693 aa of BC025378 Sequence: HPGAACAFGICCKDCKFLPSGTLCRQQVGECDLPEWCNGTSHQCPDDVYVQDGISCNVNAFCYEKTCNNHDIQCKEIFGQDARSASQSCYQEINTQGNRFGHCGIVGTTYVKCWTPDIMCGRVQCENVGVIPNLIEHSTVQQFHLNDTTCWGTDYHLGMAIPDIGEVKDGTVCGPEKICIRKKCASMVHLSQACQPKTCNMR Predict reactive species |
| Full Name | ADAM metallopeptidase domain 20 |
| Calculated Molecular Weight | 776 aa, 87 kDa |
| Observed Molecular Weight | 70-80 kDa |
| GenBank Accession Number | BC025378 |
| Gene Symbol | ADAM20 |
| Gene ID (NCBI) | 8748 |
| RRID | AB_3669344 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O43506 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
ADAM20 is the functional equivalent of sperm fertilin-alpha (ADAM1), since that gene is nonfunctional in human. And northern blot analysis detected the 2.8-kb ADAM20 mRNA only in testis. The exclusive expression of ADAM20 in human testis and their sequence similarity with the fertilins suggest that it is expressed on sperm cells and involved in sperm maturation and/or fertilization(PMID:9469942). The full length protein has a singnal peptide, propeptide and 6 glycosylation sites.
