ADSL Recombinant antibody, PBS Only

• 

  WB analysis using 86131-1-RR (same clone as 86131-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86131-1-RR (ADSL antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86131-1-PBS in a different storage buffer formulation.

ADSL Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 86131-1-PBS

Clone No.250216C6

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

AMPS, ASASE, ASL, EC:4.3.2.2

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Product Information

86131-1-PBS targets ADSL in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: ADSL fusion protein Ag7332
• Full Name: adenylosuccinate lyase
• Calculated Molecular Weight: 55 kDa
• Observed Molecular Weight: 55 kDa
• GenBank Accession Number: BC000253
• Gene Symbol: ADSL
• Gene ID (NCBI): 158
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P30566
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis and the purine nucleotide cycle, where it plays a key role in the regulation of adenosine monophosphate levels in the cells. Given its crucial role in both cellular replication and metabolism, it is not surprising that ADSL has been found dysregulated in several malignancies, including breast and endometrial cancers as well as glioma. (PMID: 33754045)