ADSL Recombinant antibody, PBS Only

ADSL Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 86131-2-PBS
Clone No.250216H4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

AMPS, ASASE, ASL, EC:4.3.2.2

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

86131-2-PBS targets ADSL in applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ADSL fusion protein Ag7332 Predict reactive species
Full Name adenylosuccinate lyase
Calculated Molecular Weight 55 kDa
Observed Molecular Weight 55 kDa
GenBank Accession NumberBC000253
Gene Symbol ADSL
Gene ID (NCBI) 158
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP30566
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.

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