AGXT2L1 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 83984-6-RR (same clone as 83984-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83984-6-RR (AGXT2L1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83984-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83984-6-RR

  Biolayer interferometry (BLl) kinetic assays of 83984-6-RR against Human AGXT2L1 were performed. The affinity constant is 5.17 nM.

AGXT2L1 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 83984-6-PBS

Clone No.241119C4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

ETNPPL, Ethanolamine-phosphate phospho-lyase, EC:4.2.3.2, Alanine--glyoxylate aminotransferase 2-like 1, 241119C4

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Product Information

83984-6-PBS targets AGXT2L1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag10584

  Product name: Recombinant human AGXT2L1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 147-499 aa of BC022526

  Sequence: IEISPYKFQKGKDVKKEFVHVAPTPDTYRGKYREDHADSASAYADEVKKIIEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEYVHGAGGVFIADEVQVGFGRVGKHFWSFQMYGEDFVPDIVTMGKPMGNGHPVACVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDIIENEDLQGNAKRVGNYLTELLKKQKAKHTLIGDIRGIGLFIGIDLVKDHLKRTPATAEAQHIIYKMKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLDRILTVLEEAMGTKTESVTSENTPCKTKMLKEAHIELLRDSTTDSKENPSRKRNGMCTDTHSLLSKRLKT

• Full Name: alanine-glyoxylate aminotransferase 2-like 1
• Calculated Molecular Weight: 499 aa, 56 kDa
• Observed Molecular Weight: 50-55 kDa
• GenBank Accession Number: BC022526
• Gene Symbol: AGXT2L1
• Gene ID (NCBI): 64850
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q8TBG4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768).