Aldolase C Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14884-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse cerebellum tissue, human heart tissue, K-562 cells, mouse brain tissue

Positive IHC detected in:
mouse brain tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2400
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aldolase C, fructose-bisphosphate

Calculated molecular weight:
39 kDa

Observed molecular weight:
40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALDOC

Synonyms
ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C
Background

Fructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).


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