|Positive WB detected in
|Western Blot (WB)
|WB : 1:500-1:1000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
16871-1-AP targets AMOTL1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|human, mouse, rat
|Host / Isotype
|Rabbit / IgG
|angiomotin like 1
|Calculated molecular weight
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Pulm Pharmacol Ther
Mitigation of tight junction protein dysfunction in lung microvascular endothelial cells with pitavastatin.
Cell Death Dis
SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1