Product Information
19533-1-AP targets ANKRD28-phospho1040S/1044S in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | ankyrin repeat domain 28 |
| Calculated Molecular Weight | 117 kDa |
| GenBank Accession Number | NM_015199 |
| Gene Symbol | ANKRD28 |
| Gene ID (NCBI) | 23243 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O15084 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ANKRD28, also named as KIAA0379 and PITK, putative to be a regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. ANKRD28 involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. ANKRD28 Targets PPP1C to modulate HNRPK phosphorylation. The antibody is to phopho-Ser1040 and Ser1044.
Publications
What published studies show
The ANKRD28-phospho1040S/1044S Polyclonal antibody (Cat# 19533-1-AP) has 1 total citation. It appears in Oncology Letters (Impact Factor 2.1), published in 2024 by Ruibin Jiang et al. The cited study investigates how SLC7A5 regulates tryptophan uptake and PD-L1 expression levels via the kynurenine pathway in ovarian cancer, placing the research field within oncology and tumor immunology.
| Species | Application | Title |
|---|---|---|
Oncol Lett SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer |
