Product Information
18717-1-AP targets ANTXR1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | anthrax toxin receptor 1 |
| Calculated Molecular Weight | 63 kDa |
| GenBank Accession Number | NM_032208 |
| Gene Symbol | ANTXR1 |
| Gene ID (NCBI) | 84168 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H6X2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ANTXR1, also named as ATR and TEM8, is type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. It has been shown to be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. It is highly expressed in tumor endothelial cells. The antibody only recognizes the isoform 1 of ANTXR1.
