ANXA2R Polyclonal antibody

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  IHC staining of human prostate cancer using 23838-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 10x lens).

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  IHC staining of human prostate cancer using 23838-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 40x lens).

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  IHC staining of human brain using 23838-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human brain using 23838-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 23838-1-AP (ANXA2R antibody at dilution of 1:50 (under 40x lens).

ANXA2R Polyclonal Antibody for IHC, ELISA

Cat No. 23838-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

Synonyms

C5orf39, Annexin 2 receptor, Annexin II receptor, Annexin-2 receptor, AX2R

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Tested Applications

• Positive IHC detected in: human prostate cancer tissue, human brain tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

23838-1-AP targets ANXA2R in WB, IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag20807

  Product name: Recombinant human C5orf39 protein

  Source: e coli.-derived, PET30a

  Tag: 6*His

  Domain: 1-193 aa of BC067873

  Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLRQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP

• Full Name: chromosome 5 open reading frame 39
• Calculated Molecular Weight: 193 aa, 22 kDa
• GenBank Accession Number: BC067873
• Gene Symbol: ANXA2R
• Gene ID (NCBI): 389289
• RRID: AB_2879333
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen Affinity purified
• UNIPROT ID: Q3ZCQ2
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ANXA2R (annexin A2 receptor) is a receptor protein that interacts with annexin A2 (ANXA2). ANXA2R plays significant roles in various diseases. For instance, in renal cell carcinoma (RCC), high expression of ANXA2R is associated with poor prognosis. A recent study published in Nature revealed that SP140 regulates interferon mRNA stability and antiviral immunity by inhibiting a novel regulator, RESIST, which decreases the stability of Ifnb1 mRNA and thereby suppresses interferon expression. Notably, RESIST is the orthologue of human ANXA2R. This finding highlights the crucial role of ANXA2R in cellular signaling and immune responses.

Publications

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Biochem Biophys Res Commun; CircRNA circ-0038718 promotes hepatocellular carcinoma progression through sponging miR-139-3p.; Authors - Ranran Sun