APBA1 Polyclonal antibody, PBS Only

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• APBA1 Polyclonal antibody, PBS Only (55089-1-PBS)

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  WB analysis using 55089-1-AP (same clone as 55089-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55089-1-AP (APBA1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55089-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 55089-1-AP (same clone as 55089-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 55089-1-AP (APBA1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55089-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 55089-1-AP (same clone as 55089-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 55089-1-AP (APBA1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55089-1-PBS in a different storage buffer formulation.

APBA1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 55089-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

X11, Neuron specific X11 protein, MINT1, Mint 1, D9S411E

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Product Information

55089-1-PBS targets APBA1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: amyloid beta (A4) precursor protein-binding, family A, member 1
• Calculated Molecular Weight: 93 kDa
• Observed Molecular Weight: 138-140 kDa
• GenBank Accession Number: NM_001163
• Gene Symbol: APBA1
• Gene ID (NCBI): 320
• RRID: AB_3670237
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q02410
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

APBA1, also named MINT1 and X11A, is a brain-specific multi-modular protein that interacts with the Alzheimer's disease amyloid precursor protein (APP)(PMID: 22136355). APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. APBA1 is expressed in the brain and was found to interact with Munc18.