ARHGAP5 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55165-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HepG2 cells, Jurkat cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
Rho GTPase activating protein 5

Calculated molecular weight:
172 kDa

Observed molecular weight:
170-190 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARHGAP5

Synonyms
ARHGAP5, GFI2, p190 B, RhoGAP5
Background

ARHGAP5, also named as RHOGAP5 and p190-B, is GTPase-activating protein for Rho family members. It may play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. ARHGAP5 can be directly phosphorylated on a single identified tyrosine residue by the activated insulin and IGF-1 receptors. It also has been shown to be tyrosine phosphorylated by cSrc and vSrc. Additionally the GAP domain of ARHGAP5 is shown to attenuate signal transducing activity of Rac, Rho and CDC42. The antibody is specific to ARHGAP5.


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